FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Osborne, Jr. Charles F
   2. Issuer Name and Ticker or Trading Symbol
SCYNEXIS INC [SCYX] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Financial Officer
(Last)
(First)
(Middle)
C/O SCYNEXIS, INC., 3501 C TRICENTER BOULEVARD		 3. Date of Earliest Transaction (Month/Day/Year)
06/18/2014
(Street)

DURHAM, NC 27713		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) $ 9.64 06/18/2014   A   960     (1) 06/17/2024 Common Stock 960 (2) 960 D  
Stock Option (right to buy) $ 20.4 06/18/2014   D     960   (1) 10/21/2014 Common Stock 960 (2) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   934     (1) 06/17/2024 Common Stock 934 (2) 934 D  
Stock Option (right to buy) $ 20.4 06/18/2014   D     934   (1) 04/27/2015 Common Stock 934 (2) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   490     (1) 06/17/2024 Common Stock 490 (2) 490 D  
Stock Option (right to buy) $ 20.4 06/18/2014   D     490   (1) 04/19/2016 Common Stock 490 (2) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   1,225     (1) 06/17/2024 Common Stock 1,225 (2) 1,225 D  
Stock Option (right to buy) $ 20.4 06/18/2014   D     1,225   (1) 04/25/2017 Common Stock 1,225 (2) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   808     (1) 06/17/2024 Common Stock 808 (2) 808 D  
Stock Option (right to buy) $ 20.4 06/18/2014   D     808   (1) 04/17/2018 Common Stock 808 (2) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   1,225     (1) 06/17/2024 Common Stock 1,225 (2) 1,225 D  
Stock Option (right to buy) $ 25.5 06/18/2014   D     1,225   (1) 04/22/2019 Common Stock 1,225 (2) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   1,470     (1) 06/17/2024 Common Stock 1,470 (3) 1,470 D  
Stock Option (right to buy) $ 25.91 06/18/2014   D     1,470   (1) 07/14/2020 Common Stock 1,470 (3) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   833     (1) 06/17/2024 Common Stock 833 (3) 833 D  
Stock Option (right to buy) $ 30.6 06/18/2014   D     833   (1) 04/20/2020 Common Stock 833 (3) 0 D  
Stock Option (right to buy) $ 9.64 06/18/2014   A   57,420     (4) 06/17/2024 Common Stock 57,420 $ 0 57,420 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Osborne, Jr. Charles F
C/O SCYNEXIS, INC.
3501 C TRICENTER BOULEVARD
DURHAM, NC 27713		       Chief Financial Officer  

Signatures

 /s/ Eileen Pruette, by power of attorney   06/19/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The option is fully vested.
(2) The re-pricing of the option is subject to the approval of the Company's stockholders. In connection with the re-pricing of the option, the option was further amended to provide that the term of the option shall be extended until June 17, 2024 and, in the event of the holder's termination of services with the Company, the holder shall have the right to exercise any vested shares under the option until the expiration of the option. In connection with the amendments, the original option is deemed canceled and replaced with a new option.
(3) In connection with the re-pricing of the option, the option was further amended to provide that the term of the option shall be extended until June 17, 2024. In connection with the amendments, the original option is deemed canceled and replaced with a new option.
(4) The option vests in 48 equal monthly installments from the grant date of June 18, 2014.

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