Ownership Submission

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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3235-0104

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(Print or Type Responses)

1. Name and Address of Reporting Person ^*

Nothias Jean-Yves

2. Date of Event Requiring Statement (Month/Day/Year)
05/02/2014

3. Issuer Name and Ticker or Trading Symbol
SCYNEXIS INC [SCYX]

(Last)

(First)

(Middle)

C/O SCYNEXIS, INC.,, 3501 C TRICENTER BOULEVARD

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

__X__ Director	_____ 10% Owner
_____ Officer (give title below)	_____ Other (specify below)

5. If Amendment, Date Original Filed(Month/Day/Year)

(Street)

DURHAM, NC 27713

6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

(City)

(State)

(Zip)

Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security
(Instr. 4)

2. Amount of Securities Beneficially Owned
(Instr. 4)

3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)

4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
	Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security		6. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock Warrant (right to buy)	12/07/2011	12/06/2016	Common Stock	5,251 ⁽¹⁾	$ 0.2	I	By FCPR Biotechnology Fund
Common Stock Warrant (right to buy)	05/15/2012	05/14/2017	Common Stock	5,251 ⁽¹⁾	$ 0.2	I	By FCPR Biotechnology Fund
Common Stock Warrant (right to buy)	12/11/2013	12/10/2018	Common Stock	25,998 ⁽¹⁾	$ 0.2	I	By FCPR Biotechnology Fund
Series B Preferred Stock	08/24/2000	⁽²⁾	Common Stock	46,863 ⁽¹⁾ ⁽²⁾	$ ⁽²⁾	I	By FCPR Biotechnology Fund
Series C Preferred Stock	06/19/2002	⁽³⁾	Common Stock	88,796 ⁽¹⁾ ⁽³⁾	$ ⁽³⁾	I	By FCPR Biotechnology Fund
Series D-1 Preferred Stock	12/11/2013	⁽⁴⁾	Common Stock	42,336 ⁽¹⁾ ⁽⁴⁾	$ ⁽⁴⁾	I	By FCPR Biotechnology Fund
Series D-2 Preferred Stock	12/11/2013	⁽⁵⁾	Common Stock	30,582 ⁽¹⁾ ⁽⁵⁾	$ ⁽⁵⁾	I	By FCPR Biotechnology Fund

Reporting Owners

Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
Nothias Jean-Yves C/O SCYNEXIS, INC., 3501 C TRICENTER BOULEVARD DURHAM, NC 27713	X

Signatures

/s/ Eileen Pruette, by power of attorney		05/02/2014
^**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The reporting person disclaims beneficial ownership of the reported securities except to the extent of his pecuniary interest therein.
(2)	Each of the Series B Preferred Stock is convertible into Common Stock of the Issuer on a 1-for-3.536 basis at any time at the holder's election, and automatically upon the closing of the Issuer's initial public offering, and has no expiration date.
(3)	Each of the Series C Preferred Stock is convertible into Common Stock of the Issuer on a 1-for-3.536 basis at any time at the holder's election, and automatically upon the closing of the Issuer's initial public offering, and has no expiration date.
(4)	Each of the Series D-1 Preferred Stock is convertible into Common Stock of the Issuer on a 1-for-20.4 basis at any time at the holder's election, and automatically upon the closing of the Issuer's initial public offering, and has no expiration date.
(5)	Each of the Series D-2 Preferred Stock is convertible into Common Stock of the Issuer on a 1-for-20.4 basis at any time at the holder's election, and automatically upon the closing of the Issuer's initial public offering, and has no expiration date.

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