Ownership Submission

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person ^*

Ribeill Yves J

2. Date of Event Requiring Statement (Month/Day/Year)
05/02/2014

3. Issuer Name and Ticker or Trading Symbol
SCYNEXIS INC [SCYX]

(Last)

(First)

(Middle)

C/O SCYNEXIS, INC.,, 3501 C TRICENTER BOULEVARD

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

__X__ Director	_____ 10% Owner
__X__ Officer (give title below)	_____ Other (specify below)
President and CEO

5. If Amendment, Date Original Filed(Month/Day/Year)

(Street)

DURHAM, NC 27713

6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

(City)

(State)

(Zip)

Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	16,975	D

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security		6. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock Warrant (right to buy)	01/31/2014	01/30/2019	Common Stock	595	$ 0.2	D
Series D-2 Preferred Stock	12/11/2013	⁽¹⁾	Common Stock	595 ⁽¹⁾	$ ⁽¹⁾	D
Stock Option (right to buy)	⁽²⁾	10/21/2014	Common Stock	7,352	$ 20.4	D
Stock Option (right to buy)	⁽²⁾	04/27/2015	Common Stock	7,352	$ 20.4	D
Stock Option (right to buy)	⁽²⁾	04/19/2016	Common Stock	931	$ 20.4	D
Stock Option (right to buy)	⁽²⁾	04/25/2017	Common Stock	3,676	$ 20.4	D
Stock Option (right to buy)	⁽²⁾	04/17/2018	Common Stock	2,941	$ 20.4	D
Stock Option (right to buy)	⁽²⁾	04/22/2019	Common Stock	3,676	$ 25.5	D
Stock Option (right to buy)	⁽²⁾	07/14/2020	Common Stock	2,941	$ 25.91	D
Stock Option (right to buy)	⁽²⁾	04/20/2021	Common Stock	1,960	$ 30.6	D

Reporting Owners

Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
Ribeill Yves J C/O SCYNEXIS, INC., 3501 C TRICENTER BOULEVARD DURHAM, NC 27713	X		President and CEO

Signatures

/s/ Eileen Pruette, by power of attorney		05/02/2014
^**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The Series D-2 Preferred Stock is convertible into Common Stock of the Issuer on a 1-for-20.4 basis at any time at the holder's election, and automatically upon the closing of the Issuer's initial public offering, and has no expiration date.
(2)	The option vests and becomes exercisable with respect to 25% of the total number of underlying shares on each the first and the second anniversary of the vesting commencement date and with respect to the remaining 50% of the underlying shares on the third anniversary of the vesting commencement date.

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