Exhibit 10.28

PATENT ASSIGNMENT

THIS PATENT ASSIGNMENT is executed by Merck Sharp & Dohme Corp., a New Jersey corporation with a principal place of business at One Merck Drive, Whitehouse Station, New Jersey 08889 (“Assignor”) for the benefit of Scynexis, Inc., a Delaware corporation with a principal place of business at 3501 C Tricenter Boulevard, Durham, NC 27713 (“Assignee”).

RECITALS

Whereas, the Assignor owns certain rights, title and interest in, to and under the patents set forth in the Patent Schedule attached hereto (“the Patents”), each of which is related to enfumafungin.

Whereas, the Assignee is desirous of acquiring or confirming all of Assignor’s rights, title and interest in, to and under the Patents.

To effect such transactions and in consideration of the foregoing and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, and intending to be legal bound hereby, the parties agree as follows:

TERMS

Section 1 Assignment. The Assignor hereby conveys, transfers, assigns to, and confirms in the Assignee its entire right, title and interest in, to and under the Patents, any continuation, divisional and continuation-in-part patent applications directed to the same invention as, and claiming priority to, the Patents, as well as any patents that issue therefrom including all extensions, renewals, reissues, reexaminations and foreign counterparts thereof.

Section 2 Prosecution, Maintenance, and Enforcement Responsibilities.

Assignee shall assume and be responsible for prosecuting, maintaining and enforcing the Patents assigned herein.

Section 3 Assignment Recordation. The responsibility and cost of recording the present instrument assignment the Patents assigned herein or any assignment of any other patent applications arising from the Patents shall be borne solely by Assignee.

[Signature Page Follows]

IN WITNESS WHEREOF, the parties have caused this Patent Assignment to be executed as of the date written below.

Executed this 28^th day of January, in the year 2014.

At

State of     Pennsylvania    

County of     Montgomery    

Before me personally appeared Iain D. Dukes who acknowledged the foregoing instrument to be a free act and deed and also represented that he is a Senior Vice President, Worldwide Licensing and External Research at Merck Sharp & Dohme Corp., and is authorized to execute [and seal] the same this 28 day of January, in the year 2014.

PATENT SCHEDULE

TITLE:        ANTIFUNGAL AGENT

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PATENT SCHEDULE

TITLE:        ANTIFUNGAL AGENTS

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PATENT SCHEDULE

TITLE:        ANTIFUNGAL AGENTS

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PATENT SCHEDULE

TITLE:        ANTIFUNGAL AGENTS

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