Holder Shares Held % O/S Share Change Filing Date
Federated Hermes, Inc. 19,099,300 19.6 488,888 3/31/20
Caxton Associates LP 7,936,111 8.1 - 3/31/20
Armistice Capital LLC 6,222,778 6.4 - 3/31/20
Decheng Capital LLC 5,555,556 5.7 - 3/31/20
The Vanguard Group, Inc. 2,795,734 2.9 24,055 3/31/20
Kingdon Capital Management, LLC 2,670,487 2.7 376,043 3/31/20
Broadfin Capital, LLC 2,000,000 2.1 - 3/31/20
BlackRock, Inc. 952,793 1.0 101,957 3/31/20
Medical Strategy GmbH, Asset Mgmt 706,681 0.7 - 3/31/20
Geode Capital Management, L.L.C. 642,257 0.7 104805 3/31/20
BBVA Asset Management, S.A. 500,000 0.5 500,000 3/31/20
Renaissance Technologies LLC 451,760 0.5 (235,637) 3/31/20
Connor, Clark & Lunn Investment Mgmt 229,964 0.2 180,314 3/31/20
Creative Planning, Inc. 202,000 0.2 35,000 3/31/20
California Public Employees' Retirement System 200,000 0.2 - 3/31/20